Chicken Alfredo Casserole

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Learn how to make the ultimate chicken alfredo casserole that’s rich, creamy, and packed with flavor. This easy-to-make dish features juicy chicken bites, tender broccoli florets, and a luscious, homemade alfredo sauce that ties it all together. Perfect for a cozy family dinner or meal prep, this low-carb casserole is a satisfying comfort food that everyone will love.

This chicken alfredo casserole is made with just a handful of simple ingredients and baked to creamy, cheesy perfection. It’s the ideal weeknight dinner—quick to prepare, comforting, and guaranteed to please the whole family.

If you’re searching for a hearty, crowd-pleasing meal that feels indulgent but is easy enough for any night of the week, this recipe is for you. Just layer the ingredients, bake until bubbly, and gather your loved ones around the table to enjoy a dish that tastes like it came from your favorite Italian restaurant.

Cheesy casserole recipes are some of my all-time favorites because they’re simple, versatile, and always hit the spot. Whether I’m making chicken cordon bleu casserole, green bean casserole, or this rich and creamy chicken alfredo casserole, my family always asks for seconds.

What Is Chicken Alfredo Casserole?

Chicken Alfredo Casserole is a comforting, creamy baked dish made with tender chicken breast, cooked pasta, melty cheese, and a rich, homemade Alfredo sauce. Everything is combined in one dish, then topped with extra cheese and baked until golden, bubbly, and irresistibly delicious.

This easy-to-make casserole brings together the classic flavors of Chicken Alfredo pasta in a warm, oven-baked version that’s perfect for busy weeknights or cozy weekend dinners.

While the base recipe is simple and satisfying, it’s also versatile—you can mix in extras like:

• Steamed broccoli or spinach for added nutrients and color
• Crispy bacon for a smoky twist
• Fresh herbs like parsley or basil to brighten the flavor

Whether you’re making it for a family meal, a potluck, or a special occasion, chicken Alfredo casserole is a hearty and satisfying dish that always impresses.

Can I Make Low Carb Chicken Alfredo Casserole?

Absolutely! Low carb chicken Alfredo casserole is a delicious and lighter alternative to the traditional version—perfect for those following a keto or low-carb lifestyle. This healthy chicken casserole still delivers all the creamy, cheesy flavor you love, but without the carbs from regular pasta.

Instead of using high-carb noodles, this version swaps in tender broccoli florets or other low-carb vegetables like cauliflower or zucchini. The result is a nutritious, filling dish that’s rich in protein, loaded with flavor, and totally satisfying.

This keto chicken Alfredo casserole is:

• Grain-free and gluten-free
• Easy to prep ahead for busy weeknights
• A family-friendly meal even non-keto eaters will enjoy
• Perfect for meal prep—just reheat and serve!

Whether you’re looking for a comforting low-carb dinner or a crowd-pleasing casserole that’s easy on carbs but big on taste, this dish checks all the boxes.

Why You’re Going to Love This Chicken Alfredo Casserole

This chicken Alfredo casserole is everything you want in a comforting, satisfying meal—and more. It’s rich, creamy, cheesy, and incredibly easy to put together, making it perfect for both busy weeknights and relaxed weekend dinners.

Here’s why you’ll love this recipe:

• Family-Friendly Favorite – A crowd-pleasing dinner that both kids and adults will devour.
• Quick and Easy to Prepare – Simple ingredients and minimal prep make this an ideal go-to meal.
• Ready in Under 40 Minutes – From start to finish, you’ll have a delicious meal on the table fast.
• Make-Ahead Friendly – Prepare it in advance and bake it when ready. Great for meal planning and freezer meals.
• Customizable and Versatile – Add your favorite low-carb vegetables like spinach, mushrooms, or cauliflower. Swap cheeses or use rotisserie chicken for convenience.
• A Delicious Way to Eat More Veggies – The creamy Alfredo sauce makes it easy to sneak in extra vegetables without sacrificing taste.
• Perfect for Low-Carb or Keto Diets – Easily adapt the recipe by using broccoli or cauliflower instead of pasta for a keto chicken Alfredo casserole.
• Great for Leftovers – It reheats beautifully, making it an excellent option for lunch the next day.

Ingredients for Chicken Alfredo Casserole

To make this comforting and delicious chicken Alfredo casserole, you’ll only need a handful of easy-to-find ingredients—many of which you likely already have in your kitchen. This recipe is simple, flavorful, and perfect for a hearty family meal. Here’s what you’ll need:

• Broccoli – A low-carb vegetable that works perfectly as a substitute for pasta in this dish. It’s high in fiber, vitamins, and minerals, and its mild flavor pairs beautifully with chicken and creamy Alfredo sauce.
• Chicken Breast – Use cooked boneless, skinless chicken breast, diced or shredded. You can also substitute with chicken thighs or use leftover rotisserie chicken to save time.
• Onion and Garlic Powder – These pantry staples add depth of flavor. For a more intense taste, feel free to use fresh minced garlic or sautéed onions.
• Olive Oil – Used for sautéing or lightly coating the vegetables. You can substitute with avocado oil or any neutral vegetable oil you prefer.
• Alfredo Sauce – A creamy, rich sauce that brings everything together. Use your favorite store-bought keto-friendly Alfredo sauce, or try our homemade Alfredo sauce for extra flavor and control over ingredients.
• Mozzarella Cheese – Adds that gooey, melty goodness on top. You can also use a blend of cheeses like cheddar, provolone, or parmesan depending on your flavor preferences.

How to Make Chicken Alfredo Casserole

Once you see how simple and satisfying it is to prepare this creamy chicken Alfredo casserole, it’ll quickly become one of your go-to recipes for busy weeknights or cozy family dinners.

Follow these easy steps:

Cook The Chicken 

Cut the chicken breast into 1-inch cubes and season them with onion powder, garlic powder, salt, and pepper.

Heat the olive oil in a large skillet over medium-high heat and cook the chicken bites for about 5 minutes on each side until golden brown.

Prepare The Broccoli

While the chicken is cooking, cut the broccoli into bite-size florets.

Assemble The Casserole

Spread ½ cup of keto alfredo sauce on the bottom of a casserole dish. Then add the cooked chicken and broccoli florets.

Top with the rest of the alfredo sauce and mix until everything is well combined.

Sprinkle the mozzarella cheese on top of the casserole.

Bake the Casserole

Bake uncovered for 25–30 minutes, or until the cheese is melted and bubbly, and the top is golden brown.

Serve and Enjoy

Garnish with fresh chopped parsley before serving.

Serve hot and enjoy this rich, cheesy, and satisfying low-carb chicken Alfredo bake with your family or guests.

Tips for the Best Chicken Alfredo Casserole

To make sure your chicken Alfredo casserole turns out perfectly creamy, flavorful, and satisfying every time, keep these helpful tips and variations in mind:

• Don’t Overbake. Overbaking can dry out the chicken and turn your broccoli mushy. Bake just until the cheese is melted and bubbly, and the top is lightly golden—typically 25–30 minutes is ideal.
• Use Fresh or Lightly Steamed Veggies. Using fresh broccoli adds a nice texture, but if you prefer it softer, steam or blanch it briefly before adding. You can also mix in other low-carb vegetables like: cauliflower florets, sautéed mushrooms, spinach or kale, bell peppers for a sweet crunch and added color.
• Add a Kick of Heat. For a spicy chicken Alfredo casserole, stir in 1 tablespoon of red pepper chili flakes or a dash of hot sauce into the Alfredo sauce before baking.
• Add a Crispy Topping. For a golden, crispy crust, sprinkle grated Parmesan and a few tablespoons of keto-friendly breadcrumbs (or crushed pork rinds for low-carb) over the top before baking.
• Use Pre-Cooked or Rotisserie Chicken. Save time by using leftover shredded chicken or store-bought rotisserie chicken—a quick and delicious shortcut that works great for meal prep.
• Let It Rest Before Serving. Allow the casserole to sit for 5 minutes after baking. This helps the sauce thicken slightly and makes serving cleaner and easier.

Variations

• Spinach and Artichoke: Add chopped spinach and canned artichoke hearts to the casserole.
• Buffalo Chicken: Use buffalo sauce and shredded chicken to add a spicy kick.
• Sun-Dried Tomato: Add chopped sun-dried tomatoes to the casserole.
• Mexican Chicken: Use taco seasoning, corn, and black beans.
• Pesto: Mix in some pesto sauce for an herby and flavorful twist on the classic casserole.
• Greek Chicken: Use Greek seasoning, kalamata olives, and feta cheese to add a Mediterranean twist to the casserole.

Serving Ideas

Even if this chicken alfredo casserole is enough to create dinner on its own, you can also pair it with delicious side dishes. Here are some great ideas:

• Cauliflower Risotto
• Best Creamy Cauliflower Mashed Potatoes
• A green salad
• Air Fryer Sweet Potato Fries Recipe

Storing Ideas

• Fridge: If there are any chicken alfredo casserole leftovers, you can store them in the fridge in an airtight container for up to 5 days.
• Freezer: You can also freeze the casserole leftovers in an airtight freezer-safe container for up to one month. Defrost overnight in the refrigerator before reheating in the oven or microwave.

What’s the Best Casserole Dish to Use?

For the perfect chicken Alfredo casserole, the right dish can make a big difference in how evenly your casserole cooks and how beautifully it serves.

Best Size & Material

• A 9×13-inch (3-quart) baking dish is ideal for this recipe. It provides enough space for all the ingredients to bake evenly without overflowing.
• Use a glass or ceramic casserole dish for even heat distribution and a beautiful presentation if you’re serving it straight from the oven to the table.
• For quicker cleanup, opt for a non-stick or enameled cast iron baking dish—these retain heat well and can go from oven to table seamlessly.

Bonus Tip:

If you like crispy, golden cheese edges, use a shallow baking dish that allows more surface area to brown. For a deeper, creamier casserole, a deeper dish will give you those layered textures.

Can I Make This Recipe Ahead Of Time?

Sure, you can make this easy casserole recipe ahead. Just prepare all the ingredients and assemble the casserole ahead of time.

Then wrap it well with plastic foil and freeze it for a few months. 

Can I Use Leftover Chicken Breast?

Yes, actually, this recipe is great for chicken leftovers. So if you have any, chop or shred them, prepare the rest of the ingredients, assemble, and bake the casserole.

More Casserole Recipes

• Keto Green Bean Casserole
• Keto Sweet Potato Casserole
• Chicken Cordon Bleu Casserole